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Glycoproteins - Structure and Function

Code: 152834
ECTS: 5.0
Lecturers in charge: prof. dr. sc. Vladimir Mrša
Take exam: Studomat
Load:

1. komponenta

Lecture typeTotal
Lectures 10
Seminar 5
* Load is given in academic hour (1 academic hour = 45 minutes)
Description:
Glycoprotein structure. O- and N-glycosidic linkage to proteins. Structure of O-glycosidically linked carbohydrate chains. Structure of N-glycosidically linked carbohydrate chains.Biosynthesis of O-glycosidically linked carbohydrate chains. Biosynthesis of N-glycosidically linked carbohydrate chains. Control of protein glycosylation. Role and importance of protein glycosylation. Reversibile glycosylation.
Literature:
  1. OBVEZNA LITERATURA:
    B.Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter, Molecular biology of the cell 4th ed., Garland Publishing, Inc., New York 2002.
    T.W. Rademacher, R.B. Parekh, R.A. Dwek: Glycobiology, u: Ann. Rev. Biochem. 57 (1988) 785.
    N. Sharon, Trends Biochem. Sci. 9 (1984) 198.
    T.L. Doering, W.J. Masterson, G.W. Hart, P.T. Englund, J. Biol. Chem. 265 (1990) 611.
    M. Genzsch, W. Tanner, EMBO J., 15 (1996) 5752-5759.
    H. Nothaft, C. M. Szymanski, Nature Rev. Microbiol. 8 (2010) 765-778.
    K. Marino, J. Bones, J. J. Kattla, P. M. Rudd, Nature Chem. Biol. Rev. 6 (2010) 713-723.
  2. DOPUNSKA LITERATURA:
    revijalni članci i znanstvene monografije
1. semester
Izborni kolegiji za smjer analitička kemija - Regular study - Analytical chemistry
Izborni kolegiji za smjer biokemija - Regular study - Biochemistry
Izborni kolegiji za smjer anorganska i strukturna kemija - Regular study - Inorganic and structural chemistry
Izborni kolegiji za smjer organska kemija - Regular study - Organic chemistry
Izborni kolegiji za smjer fizikalna kemija - Regular study - Physical chemistry

3. semester
Izborni predmeti doktorski studij kemije - Regular study - Analytical chemistry
Izborni predmeti doktorski studij kemije - Regular study - Biochemistry
Izborni predmeti doktorski studij kemije - Regular study - Inorganic and structural chemistry
Izborni predmeti doktorski studij kemije - Regular study - Organic chemistry
Izborni predmeti doktorski studij kemije - Regular study - Physical chemistry
Consultations schedule: