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Organic chemistry 1
 
Organic chemistry 1
 
Code: 40764
ECTS: 6.0
Lecturers in charge: doc. dr. sc. Ivana Biljan - Lectures
Lecturers: Danijela Mihelec - Exercises
Take exam: Studomat
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1. komponenta

Lecture typeTotal
Lectures 60
Exercises 15
* Load is given in academic hour (1 academic hour = 45 minutes)
Description:
COURSE GOALS: Introduction to structure and reactivity of carbon compounds.

LEARNING OUTCOMES AT THE LEVEL OF THE PROGRAMME:
1. KNOWLEDGE AND UNDERSTANDING
1.2. demonstrate a thorough knowledge and understanding of the fundamental concepts in chemistry
1.4. demonstrate a thorough knowledge and understanding of the most important chemistry laws and theories
2. APPLYING KNOWLEDGE AND UNDERSTANDING
2.2. describe important aspects of chemical change
2.4. recognize and follow the logic of arguments, evaluate the adequacy of arguments and construct well supported arguments
5. LEARNING SKILLS
5.1. search for and use professional literature as well as any other sources of relevant information

LEARNING OUTCOMES SPECIFIC FOR THE COURSE:
Students will be able to
1. identify functional groups present in organic compound and to write down its systematic name,
2. explain the basic types of bonding in chemical compounds,
3. classify and explain the isomerism of organic compounds,
4. conduct elementary conformational analysis of acyclic and cyclic organic compounds,
5. determine absolute and relative configurations of asymmetric carbon atom,
6. explain the ways the structure influences the reactivity organic species, as well as the position of chemical equilibria,
7. categorize the mechanisms of organic reactions,
8. give the details of aliphatic nucleophilic substitution mechanisms,
9. give the details of nucleophilic substitution at carbonyl group,
10. identify the carboxylic acid derivatives, and give their properties,
11. describe the principles of common spetroscopic methods used in structure determinations,
12. use spectrosopic methods to identify unknown organic compound.

COURSE DESCRIPTION:

1. Organic chemistry; A historical perspective
2. Nomenclature of organic compounds
3. Bonding in organic molecules
3.1. Early bond theory
3.2. Quantum mechanics and atomic orbitals
3.3. Molecular orbitals
3.4. Bond angles, VSEPR theory
3.5. Hybrid orbitals
3.6 Bond energies and distances
4. Acid and bases
5. Characteristic reactions of organic compounds
5.1. Reaction mechanism
5.2. Reaction energetics and kinetics
6. Stereochemistry
6.1. Classes of stereoisomers
6.2. Conformations of acyclic and cyclic compounds
6.3. Cis-trans isomerisms
6.4. Chirality, optical activity, stereoisomers characteristics and resolution
7. Structural effects on reactivity
7.1. Inductive, steric and resonance effects
7.2. The resonance method
7.3. Aromaticity
8. Nucleophilic additions to the carbonyl group; Mechanism and stereochemistry of addition
9. Nucleophilic substitutions on the carbonyl group; The carboxylic acid family
10. Nucleophilic substitutions at saturated carbon
10.1. The reaction mechanism and stereochemistry
10.2. The effects of nucleophiles, leaving groups, substrate structures, solvents, cations and neighbouring groups on reaction course
11. Alpha carbanion; alkylation of enolate anions
12. IR spectroscopy (examples of organic compounds identifications)
13. NMR Spectroscopy (structural characterization of simpler organic compounds)
14. Mass spectroscopy
15. UV spectroscopy

REQUIREMENTS FOR STUDENTS:
Regular attending of the lectures and seminars.

GRADING AND ASSESSING THE WORK OF STUDENTS:
Written problem-solving exam and oral exam of student's theoretical knowledge.
Literature:
  1. S. H. Pine, Organska kemija, Školska knjiga, 1994.
  2. L. G. Wade, Jr., Organic Chemistry, 8. izdanje, Pearson Education Inc., 2013.
Prerequisit for:
Enrollment :
Passed : General Chemistry
5. semester
Mandatory course - Mandatory studij - Physics and Chemistry Education
Consultations schedule:
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