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Neurophysiology

Code: 74432
ECTS: 6.0
Lecturers in charge: prof. dr. sc. Dubravka Hranilović
Lecturers: prof. dr. sc. Dubravka Hranilović - Seminar

dr. sc. Barbara Nikolić - Practicum
Take exam: Studomat
English level:

1,0,0

All teaching activities will be held in Croatian. However, foreign students in mixed groups will have the opportunity to attend additional office hours with the lecturer and teaching assistants in English to help master the course materials. Additionally, the lecturer will refer foreign students to the corresponding literature in English, as well as give them the possibility of taking the associated exams in English.
Load:

1. komponenta

Lecture typeTotal
Lectures 30
Practicum 15
Seminar 15
* Load is given in academic hour (1 academic hour = 45 minutes)
Description:
COURSE OBJECTIVE:
Objective of the course is to enable students to understand development, structure and function of the mammalian nervous system, with special emphasis on typically human functions.
COURSE CONTENT:
LECTURES
1) Communication between the neurons: structure of a neuron; electrical signaling; chemical signaling; types of neurotransmitters;
2) Structural and functional organization of the nervous system; Autonomous nervous system;
3) Prenatal and postnatal brain development; Evolution of brain and behavior; Brain ageing;
4) Reception of internal and external stimuli: mechanism of transduction; transforming the receptor potential into action potential; dynamic range of the receptor; receptor adaptation;
5) Audition: sound components and their perception; ear structure; auditory pathways; auditory cortex; speech and language; perception of music;
6) Vision, Gustation and Olfaction: components of picture and their perception; eye structure; visual pathways; visual cortex; olfactory and gustatory receptors, pathways and cortices;
7) Movement: reflexes and voluntary movements, motor cortex; somatosensory system and its role in movement; regeneration of the peripheral and central nervous systems;
8) Homeostatic mechanisms: autonomous nervous system; enteric nervous system, endocrine system;
9) Biological Rhythms: types of biological rhythms; molecular regulation of biological rhythms; pineal gland; physiological roles of sleep; sleep stages and brain waves; neural basis of sleep; sleep disorders;
10) Learning and memory: classifications of memory; neural circuits involved in explicit, implicit and emotional memory; brain plasticity; synaptic plasticity;
11) Cognition: aspects of cognition and brain regions involved in their control; brain asymmetry; variations in structural and functional organization of the brain; intelligence; consciousness;
12) Motivational mechanisms: causes of behavior; motivated behavior; neural regulation of behavior; hormonal regulation of behavior; emotions; examples of regulatory and non-regulatory behavior;
13) Disorders of the nervous system: neurological and behavioral disorders; neurobiological and molecular basis of the nervous system disorders; personality and its disorders;
14) Pharmacology of the nervous system: drug routes into the nervous system; agonists and antagonists of neurotransmission; molecular mechanisms of action of the psychotropic agents; tolerance, sensitization, dependence and neurotoxicity.

LABORATORY EXERCISES:
1) Nervous system: Interactive 3D display of the human central nervous system on the computer; Observing the animal nervous system preparations under a light microscope;
2) Brain: Isolation and section of the rat brain; preparation of the brain tissue for molecular analyses;
3.) Autonomous nervous system: Recording of autonomous reactions as a result of emotional reactions on the Biopac system;
4) Autonomous nervous system: Analysis and interpretation of the results;
5) Hearing: Visualization of sound and testing of its aspects with the computer program Visual Analyzer
6) Vision, smell and taste: Testing of the various aspects of the sensory perception using simple procedures (e.g. spatial organization of the taste receptors; the role of olfaction in taste determination; identification of a blind spot in a visual field, etc.);
7) Somatosensory system: Examining the function of haptic and termoreceptors, and the role of proprioreceptors in balance and movement;
8) Learning and memory: Examining various types of learning and memory by solving verbal and spatial tasks;
9)Fly School I: Connecting gene mutations with changes in learning and memory via interactive computer simulation Fly school, writing of laboratory report
10) Fly School II: individual writing of lab report;
11) Fly School III: joint analysis of the results, discussion and conclusions;
12) Pharmacology of the nervous system: Identification of the brain target regions and molecular mechanisms of the psychotropic drug action via interactive computer simulation Mouse party.

SEMINARS:
1) Mechanisms of stress resilience;
2) Molecular and cellular brain ageing;
3) Evolution of language;
4) Synesthesia;
5) Treatment of CNS-a with stem cells;
6) Consequences of sleep deprivation;
7) The effects of music on brain development and plasticity;
8) Gender differences in cognition;
9) Neurobiological basis of sexual orientation;
10) Neurobiology of social behavior;
11) Personality and its disorders;
12) Molecular mechanisms of addiction;
13) Round table on the chosen topic;
14) Pub quiz.
Literature:
  1. An Introduction to Brain and Behavior, 5th ed., Kolb B, Whishaw IQ, Campbell Teskey G, Worth Publishers, New York., 2016.
3. semester
Izborni kolegiji - Biologija čovjeka - Regular study - Molecular Biology
Consultations schedule: