About employee

prof. dr. sc. Nada Oršolić

Title: Full Professor
Public phone number:+385(0)1 4877 735
Internal phone number:105
E-mail: E-mail
Department: Division of Animal Physiology

Teaching

undergraduate

graduate

integrated undergraduate and graduate

doctoral

Predmet

Biography

  • Curriculum Vitae

     

    PERSONAL INFORMATION

                            

    Name and surname

    Nada Oršolić

    Academic title

    PhD

    Year and institution

    of PhD obtained

    1999, Department of Animal Physiology, Faculty of Science, University of Zagreb

    Address

    Rooseveltov trg 6, HR-10000 Zagreb, Croatia

    Phone

    +385(1)4877 747; +385(1)4877 735

    Fax

    +385(1)4826 260

    E-mail

    norsolic@yahoo.com; nada.orsolic@biol.pmf.hr 

    Citizenship

    Croatian

    Date and place of birth

    January 31, 1960

     

    WORK EXPERIENCE

    Date (from – until)

    26 May 1987 – today

    Institution

    Department of Animal Physiology, Faculty of Science, University of Zagreb

    Position

    Full Professor

    Work field

    Research in Cancer chemoprevention and chemotherapy, free radical biology and Cancer biochemistry, nutrition and cancer, flavonoids and anticancer drug design, Cancer immunology and cancer therapy with natural products, Natural products and diabetes, flavonoids as phytoestrogens in osteoporosis, Natural products and inflammation, Radioprotection with natural products, Cytotoxic and genotoxic effects of inhalation anesthetics, Anesthetics in combination with chemotherapy and radiotherapy,

    Date (from – until)

    2001-2002

    Institution

    MD Anderson Cancer Center (Department of Leukemia), Division of Cancer Medicine, Huston, Houston, Texas, U.S.A.

    Position

    Postdoctoral fellow

    Work field

    The possible mechanism of new antileucemic drug on parental and/or resistant cells of acute and chronic myelogenous leukemia in vitro and xenograf model in vivo.

    Date (from – until)

    Institution

     

    Position

    Work field

     

    EDUCATION

    Date

    June 18, 1999

    Place

    Zagreb

    Institution

    Faculty of Science, University of Zagreb

    Title of qualification awarded

    PhD in Biology, Molecular Biology

     

    Date

     

    July 5, 1991

    Place

    Zagreb

    Institution

    Faculty of Science, University of Zagreb

    Title of qualification awarded

    MSc in biology, Molecular Biology

     

    Date

     

    April 24, 1984

    Place

    Zagreb

    Institution

    Faculty of Science, University of Zagreb

    Title of qualification awarded

    BSc in Biology, Biology with Ecology

     

    Date

     

    March 6, 1985

    Place

    Zagreb

    Institution

    Faculty of Science, University of Zagreb

    Title of qualification awarded

    BSc in Biology

     

    LANGUAGES

    mother tongue

    Croatian

    english language

     

    speaking

    B2

    writing

    B2

    reading

    B2

     

    research and other projects

  • < >. coordinator "The effectiveness of phenolic acids on macrophage polarization, angiogenesis and tumor growth of Ehrlich asitesnog" Grants from the Croatian University

    2010-2011 Project leader for in vivo research “In vivo study of NAVS very low-aromatic rich in steranes naphtalane” The survey was conducted for the company “MEDICOPHARMACIA”, d.o.o., Topniška 4, 1000 Ljubljana.

  • 2007 - today: Project leader „Chemoprevention of tumor growth by polophenolic compounds“119-0000000-1255

  • 2007 - today: Project leader Federal Ministry of Education and Science, Bosnia and Herzegovina

  • 2007 - today: Project collaborator „Immunoadjuvant and protective effects of propolis in animals“ M

  • 2001-2006: Project collaborator «Genetic markers in animal breeding»0048105. Dr. sc. Mirko Lojkić

  • 1996 - 2002:Project collaborator M

  • 1991-1995 Project collaborator ”Experimental Hematology: differentiation and turnover of blood cells” The ministry of Science, Education and Sports Republic of Croatia No. Project: 1-08-304. Project leader: Prof. Dušan Volf

     

  • TEACHING

    Undergraduate study:

    Lecturer: Animal Physiology, Experimental animals in biological research

     

    Integrated undergraduate and graduate studies

    Lecturer: Imunology, Tumor Biology

     

    Graduate study:

    Lecturer: Immunology, Immunology and immunogenetics, Comparative Immunology, Methods in immunology, General oncology, Immunobiology of tumor and metastasis, Tumor biology, Physiology of oxidative stress in Human and Animals, Physiological mechanism in Toxicology, Ecological Immunology, Human Physiology.

     

    Postgraduate study:

    Lecturer: Chemoprevention and biotherapy of tumor, Mutagenes and antimutagens, Animal models in rodents in experimental oncology

     

    MENTORSHIPS OF DOCTORAL AND MASTER DISSERTATIONS AND TRAINING OF YOUNG RESEARCHERS AND SCIENTISTS

    Supervisor of Bachelor's degree works – 25; Supervisor for the Rectors Prize – 7; Supervisor or Co-supervisor of Final master works – 177; Supervisor of Final master science thesis (Master Dissertations) – 6; Supervisor of Final PhD thesis (Doctoral Dissertations) - 15

     

    AWARDS AND RECOGNITIONS

    Beekeeping Society of Zagreb (bronze bees)-December 6th, 2006

     

    MEMBERSHIP IN SCIENCE ORGANIZATIONS AND BODIES

    Team leader and coordinator of education at the Department of Animal Physiology, 1997-2001;  Head of laboratory facilities for breeding of animals at the Department of Animal Physiology 1999-2005 and from 2007-2013;  Team leader and coordinator of education at the Department of Animal Physiology, 2002-2009;  Member of the admission procedure at the Biology Department from 2002-2008; Member of the organizing committee for graduate studies at the Bologna Process;  Student leader for direction of a professor of biology from 2003-2009;  Head of Department of Animal Physiology from 2007-2013

     

    COMMISSIONS, COMMITTEES, BOARDS AND WORK GROUPS

    Croatian Biological Society; Croatian Immunological Society; Croatian Physiological Society; Croatian Society for Animal Science – CROLASA; 2008. Member of the Editorial Board for the journal-Journal of ApiProduct and ApiMedical Science (JAAS); 2010. Member of the Editorial Board of the journal- Bioinfo Publications; 2013 Member of the Editorial Board of the journal -Advances in Bioscience and Clinical Medicine (ABCmed)

     

    PAPERS

    CC scientific papers: 59; Other scientific papers: 65, 80 domestic and 85 international meeting abstracts

     

    Total number of publications: 84 (WOS)

    Total number of citations: 867 (WOS)

    H-index: 18 (Web of Science)

     

    Total number of publications: 75 (SCOPUS)

    Total number of citations: 905 (SCOPUS)

    H-index: 18 (SCOPUS)

     

    OTHER RESEARCH ACTIVITIES

    Reviewer -171 papers (see Attachment: N. Oršolić-Report on the scientific and professional activities)

     

    COMPUTER SKILLS

    Proficient in MS Office software package, good working knowledge of Adobe Reader, Photoshop and Illustrator, including internet electronic communication, good working knowledge of SAS programme for statistical analysis

     

    OTHER IMPORTANT SKILLS AND COMPETENCES

    In vivo studies: Can handle experimental animals like Rats, Mice, Insects, Birds, Frogs; intraperitoneal and subcutaneous injection; Dissection and excision of various organs.

    Protein Biochemistry: Western Blotting Analysis; ELISA, Separation and purification of proteins

    Cell Biology: General maintenance of cell lines; Proliferation and toxicity studies using Tritiated thymidine incorporation assay, MTS assay, clonogenic assay; micronucleus test in vitro and in vivo; Apoptosis and necrosis assay methods - Staining techniques (Propidium Iodide, AnnexinV, and Fluorescence actin staining, TUNEL TASC™ enzymatic labeling assay, DNA gel electroforesis); Determination of functional activity of macrophages, NK-cells T-and B- cells

    Molecular Biology: Genomic DNA extraction; PCR, spectrophotometric assay, comet assay

    ADDITIONAL INFORMATION AND NOTES

     

    List of publications, Supervisors, Reviewers and other scientific activities, giving a separate attachment:

    Attachment: N. Oršolić-Report on the scientific and professional activities

     

Published papers recorded in the Croatian Scientific Bibliography Database (CROSBI)

Note: this list of papers is located in an maintained by the Ruđer Bošković Institute which is in charge of the Croatian Scientific Bibliography Database (CROSBI). This link will take you to the appropriate CROSBI page of this person, containing a list of papers they have themselves entered in the database.

Show CROSBI records
For further information and for instructions on changing the above data, please contact help@bib.irb.hr.

List of select publications

  1. Oršolić N, Goluža E, Đikić D, Lisičić D, Sašilo K, Rođak E, Jeleč Ž, Vihnanek Lazarus M, Orct T. (2014) Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat" European Journal of Nutrition 53(5):1217-27.

  2. Oršolić N, Skurić J, Đikić Đ,   Stanić G. (2014) Inhibitory effect of a propolis on Di-n-Propyl Disulfide or n-Hexyl salicilate-induced skin irritation, oxidative stress and inflammatory responses in mice. Fitoterapia 93:18-30.

  3. Orsolic N, Car N.(2014) Quercetin and hyperthermia modulate cisplatin-induced DNA damage in tumor and normal tissues in vivo. Tumor Biology 35(7):6445-54.  

  4. Oršolić N. (2013) Possible Molecular Targets of Bee Venom in the Treatment of Cancer: Application and Perspectives. Forum on Immunopathological Diseases and Therapeutics, 4(3–4):275–315.

  5. Oršolić N. ( 2012) Bee venom in cancer therapy. Cancer Metastasis Rev. 31(1): 173-194.

  6. Oršolić N, Gajski G, Garaj-Vrhovac V, Dikić D, Prskalo ZŠ, Sirovina D. (2011) DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice. Eur J Pharmacol. 656(1-3):110-8.

  7. Oršolić N (2010). A review of propolis antitumor action in vivo and in vitro. Journal of ApiProduct and ApiMedical Science 2(1): 1-20.

  8. Orsolic N. (2009). Bee honey and cancer. Journal of ApiProduct and ApiMedical Science 1 (4): 93 – 103.

  9. Scientific evidence of the use of propolis in  ehtnomedicine” (Editors: Oršolić N. and Bašić I). Ethnopharmacology- Review Book, Transworld Research Network, India, 2008. 

  10. Oršolić N. and Bašić I. (2007) Cancer chemoprevention by propolis and its polyphenolic compounds in experimental animals. Phytochemistry and Pharmacology III, (Editors: V. K. Singh, J. N. Govil & C. Arunachalam, STUDIUM PRESS, LLC, U.S.A). Recent Progress in Medicinal Plants 17: 55-113.

  11. Orsolic N, Golemovic M, Quintas-Cardama A, Scappini B, Manshouri T, Chandra J, Basic I, Giles F, Kantarjian H, Verstovsek S. (2006) Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells.Cancer Sci. 97(9):952-60.

  12. Oršolić N, Giles FJ, Gourdeau H, Golemović M, Beran M, Cortes J, Freireich EJ, Kantarjian H, Verstovšek S. (2004). Troxacitabine and imatinib mesylate combination therapy of chronic myeloid leukemia:preclinical evaluation. Br. J. Haematol. 124:727-738.

  13. Oršolić N. and Bašić I. (2003) Immunomodulation by water-soluble derivative of propolis (WSDP) a factor of antitumor reactivity. J. Ethnopharmacol. 84: 265-273.