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Fundamentals of Pathophysiology

Code: 74650
ECTS: 5.0
Lecturers in charge: prof. dr. sc. Domagoj Đikić - Lectures
prof. dr. sc. Vesna Benković - Lectures
izv. prof. dr. sc. Fabijan Knežević - Lectures
Lecturers: prof. dr. sc. Vesna Benković - Seminar

izv. prof. dr. sc. Fabijan Knežević - Practicum
Take exam: Studomat
English level:


The lecturer is not able to offer courses in English at this time.

1. komponenta

Lecture typeTotal
Lectures 15
Practicum 15
Seminar 15
* Load is given in academic hour (1 academic hour = 45 minutes)
1. Define the mechanisms of disorders in physiological processes
2. Distinguish apoptosis and necrosis, atrophy and hypertrophy, and hyperplasy aplasy and their consequences
3. Describe the consequences of functional disorders of the circulatory system
4. Connect link mechanisms of the endocrine system disorders
5. Connect disorders of the digestive system and certain pathological conditions


1. Damage to cells, tissues, organs.
2. Atrophy, hypertrophy, hyperplasia, aplasia and others.
3. Cell death, apoptosis, necrosis, accumulation of disease,
4. Inflammatory reactions. Regeneration of inflammation.
5. Disorders concentration of water and electrolytes.
6. Disturbances in the supply of oxygen.
7. Disorders in local blood flow.
8. Pathophysiology of digestion.
9. Pathophysiology excretion.
10. Disturbances in the function of the endocrine system

Seminars are organized in a way to extend the topics of specific areas not covered by the lectures.

1. Pathophysiological disorders of acid-base balance and the role of compensatory mechanisms
2. Metabolic disorders, detoxification, excretion and protective functions of the liver
3. Degenerative diseases of bones and joints.
4. Pathophysiology of pregnancy and placentation abnormalities caused by gestational hypertension
5. Alzheimer's disease pathophysiology.
6. Pathophysiological basis of pain
7. Pathophysiology of brain ischemia
8. Disorders lung function and pathophysiology of asthma
9. Pathophysiology of sepsis
10. Pompe disease: pathophysiology and innovative therapeutic strategies
11. Cystic fibrosis
12. Clotting disorders and thromboembolic conditions
13. Allergies
14. Disorders of thermoregulation
15. Disorders traffic vitamins, hypervitaminosis, vitamin deficiency, development and consequences
16. Disorders, obesity, malnutrition, starvation, anorexia nervosa

Practical exercises are related to teaching units and with purpose to development of competences for the recognition of certain pathological disorders.
1. atrophy
2. hypertrophy
3. hyperplasia
4. aplasia
5. apoptosis
6. necrosis
7. inflammation
  1. S. Gamulin, M Marušić, Z Kovač i sur. Patofiziologija, Medicinska naklada Zagreb 2005
  2. O. Springer: Osnove patofiziologije (skripta) 2005, PMF Zagreb
2. semester
Izborni predmeti - Regular module - Physiology and Immunobiology
Consultations schedule: