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Physiological Mechanisms in Toxicology

Code: 83825
ECTS: 5.0
Lecturers in charge: prof. dr. sc. Domagoj Đikić - Lectures
prof. dr. sc. Nada Oršolić - Lectures
prof. dr. sc. Vesna Benković - Lectures
Lecturers: prof. dr. sc. Domagoj Đikić - Seminar

prof. dr. sc. Vesna Benković - Practicum
dr. sc. Anica Horvat Knežević - Practicum
Take exam: Studomat
English level:


The lecturer is not able to offer courses in English at this time.

1. komponenta

Lecture typeTotal
Lectures 15
Practicum 15
Seminar 15
* Load is given in academic hour (1 academic hour = 45 minutes)
Identification and acceptance of practical knowledge in toxicity testing of toxic substances and drugs, understanding of physiological processes important for analysis of toxicity data
Course themes:
1. Experimental in vivo and in vitro models in toxicology; 2.RRR principle, 3; Enzymes and biochemical pathways in toxicologic pathophysiology; 4. Standards and directives in toxicity testing, 5. Experimental design, 6. Drug toxicity testing, 7. Dose, 6. Biotransformation, 7. Apsorption, distribution, bioaccumulation, 8. citostatic drugs, 9. Nephrotoxicity, 10. Immunotoxicity, 10. Neurotoxicity, 11. Endocrine disruption, 12. Comparative toxicological models 13. Specific and systemic toxicity, 14. Toxicity of Mixtures, 15 major clases of xenobiotics
  1. Principles and Methods of Toxicology, Fifth Edition by A. Wallace Hayes (2007)
  2. Introduction to Toxicology, Third Edition by John A. Timbrell (2001)
1. semester
Izborni predmeti - Regular module - Physiology and Immunobiology
Consultations schedule: