To learn basic rules of inheritance in cells, individuals and populations; to understand the molecular mechanisms by which genes control growth, development and appearance of an organism.
1. Science of genetics: basic concept; areas of genetics, genetic discoveries. Mendelism and The Chromosomal Theory; rules of inheritance. Allelic interactions: dominance, incomplete dominance and codominance. 2. Genotyping interactions: epistasis. One Gene One Enzyme Hypothesis; Multiple alleles. 3. Sex determination; sex linkage; dosage compensation: Lyon hypothesis. 4. Linkage and mapping in eukaryotes. 5. Cytogenetics: variation in chromosome number. Mechanism and consequences. 6. Variation in chromosomal structure. Mechanism and consequences. 7. Molecular genetics: chemistry of the gene; gene expression: transcription and translation in prokaryotes and eukaryotes. 8. Gene mutations; mutation rates; point mutations, detection; DNA repair. Spontaneous and induced mutagenesis. 9. Linkage and mapping in prokaryotes and bacterial viruses. 10. Gene expression: control in prokaryotes. 11. The eukaryotic chromosome. 12. Gene expression: control in eukaryotes. 13. Non-Mendelian inheritance. 14. Quantitative and Evolutionary genetics. Population genetics.15. Recombinant DNA technology.
Include practical work in some topics with developing competences for solving and analysing genetic problems.
Laws of inheritance
Linkage in eukaryotes
Genetics of microorganisms