Sensor types, characteristics and basic principles. Signal transduction: electrochemical and optical transducers. Analyte recognition: sensing agents and methods of their immobilization. Electrochemical sensors: potentiometric sensors (ion-selective electrodes and biosensors), amperometric sensors, field-effect transistor sensors. Optical sensors based on absorption, fluorescence, attenuated total reflectance, surface plasmon resonance. Medicinal, industrial and environmental applications.
To describe the working principle of chemical sensors.
To specify the basic properties of chemical sensors.
To explain the electrochemical and optical signal transduction in chemical sensors.
To distinguish between chemical sensors with respect to the way of the analyte recognition.
To compare electrochemical sensors regarding the measured signal and the type of the selective membrane.
To explain the response mechanisms of the optical sensors.
To distinguish between biosensors with regard to an active component.
To describe the immobilization of active substances.
To compare electrochemical and optical sensors with respect to selectivity, sensitivity and response time.
To be familiar with the application of chemical sensors in medicine, industry and environmental analysis.
To design a chemical sensor for determination of an appropriate analyte.
- 1. R.F. Taylor, J.S. Schultz, Handbook of Chemical and Biological Sensors, Institute of Physics Publishing, Bristol, 1996.
2. O.S. Wolfbeis, Fiber Optic Chemical Sensors and Biosensors, CRC Press, Boca Raton, Florida, 1991.
3. R. Narayanaswamy, O.S. Wolbeis, Optical Sensors for Industrial, Environmental and Clinical Applications, Springer, 2003.