COURSE OBJECTIVES:
The main objective of the course is to introduce to students the application of mathematics, statistics and computational science in quantitative biology.
COURSE CONTENT:
1. Population and quantitative genetics - Heritability and its applications,
2. Molecular evolution - Molecular phylogenetics methods and their applications,
3. Tumours, Communication of tumour and tumour microenvironment, Correlation studies, Model making,
4. Ecotoxicology - Anthropogenic compounds in aquatic ecosystems: quantitative assessment of negative impacts,
5. Computational biology - Next generation sequencing and metagenomics,
6. Biophysics - Models in biophysics of cell division,
7. Ecology - Vegetation science and spatial data,
8. Biodiversity - Classification systems, numerical taxonomy and phenetic approach,
9. Evolutionary genomics - Introduction to phylostratigraphy and its applications.
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Latest papers in the high-profile journals that cover specific topics in the syllabus.
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The origins of genome architecture, Lynch, M., Sinauer Associates, 2007.
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Introduction to quantitative genetics, Falconer, D. S. & Mackay, T. F. C, Pearson, Prentice Hall, 2009.
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Quantitative Biology Theory, Computational Methods, and Models Edited by Brian Munsky, William S. Hlavacek and Lev S. Tsimring, 2018.
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Numerical taxonomy. The principles and practice of numerical classification, Sneath, P. H., & Sokal, R. R., Springer, 1973.
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Biometry: the principles and practice of statistics in biological research, Rohlf, F. J., & Sokal, R. R., New York: Freeman, 1981.
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Numerical ecology, Legendre, P., & Legendre, L. F., Elsevier, 2012.
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Spatial analysis: a guide for ecologists, Dale, M. R., & Fortin, M. J., Cambridge University Press, 2014.
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