Postovani,
prosljedjujem oglas u kojem kolega iz Belgije (Rob Jelier, KU Leuven) trazi PhD studenta za rad na istrazivanju veze genotipa i fenotipa kvasca.
Koliko razumijem, trazi se biolog sa odredjenim racunalnim predznanjem ili racunarac/matematicar/fizicar sa afinitetom za biologiju.
Slobodno proslijedite oglas i drugim potencijalno zainteresiranima.
Srdacan pozdrav,
Fran Supek
--
Fran Supek, PhD
postdoctoral researcher, Marie Curie fellow Lehner and Gabaldon Groups CRG - Centre for Genomic Regulation Barcelona, Spain
Predicting a phenotype from its genotype: whole genome reverse
genetic predictions
This is a project within the Centre of Microbial and Plant Genetics of the
KU Leuven.
Project
Understanding the relationship between an organism’s genotype and
phenotype is one of biology’s fundamental challenges. In this
predominantly computational PhD project, the budding yeast will be used
as a model organism to better understand two complex genetic traits:
ethanol and high temperature resistance. Based on whole genome
sequences, both natural variation and mutations arising in experimental
evolution will be correlated with phenotypes. An immediate challenge in
the project will be to develop approaches to determine which of the many
variants in these genomes are having functional effects. Later, the focus
will be on unraveling and predicting epistatic interactions between alleles,
for example by working with functional gene networks that are based on a
combination of published data. In this project, the student will collaborate
with a leading yeast lab, which will generate data by high-throughput
sequencing of DNA and mRNA of yeast populations and isolates.
Profile
For this position we are looking for an aspiring computational biology
scientist, preferably with experience in machine learning, handling large
biological datasets and statistical tools such as R. Advanced command of
both spoken and written English is mandatory. The applicant should hold
a degree that formally qualifies him/her to enter the PhD program of the
Leuven Arenberg Doctoral School (http://set.kuleuven.be/phd/).
Offer
KU Leuven is a leading research-intensive, internationally oriented
university that carries out both fundamental and applied research. It is
strongly inter- and multidisciplinary in focus and strives for international
excellence. The successful candidate will receive an attractive salary and
multiple benefits (including health insurance, access to university
infrastructure and sports facilities, etc.).
Applicants should submit a letter of motivation, a detailed Curriculum
Vitae and two (academic) reference letters, to Rob Jelier
(Rob.Jelier@biw.kuleuven.be).
Pristupačnost
